RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
Isg20
RNA ID
ENSMUSG00000039236
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
RT-qRT-PCR;western blot;luciferase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
33939247
Title
LncRNA lnc-ISG20 promotes renal fibrosis in diabetic nephropathy by inducing AKT phosphorylation through miR-486-5p/NFAT5
Year
2021
Function
Lnc-ISG20 promotes the renal fibrosis process in diabetic nephropathy by activating AKT through the miR-486-5p/NFAT5 axis.